生存和死亡的COVID-19患者之间的CBC差异:一个队列研究
Mahboobeh Freidoon1, Narjes Soleimanifar2, Naghmeh Sayadi1
1Nephrology Department of Shohaday-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Medical journal of the Islamic Republic of Iran
|November 29, 2023
概括
完整血清 (CBC) 测试可以预测冠状病毒疾病2019 (COVID-19) 的预后. 较低的白细胞 (WBC) 和淋巴细胞计数,以及较高的中性粒细胞计数,表明COVID-19的结果不佳.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 临床病理学 临床病理学
背景情况:
- 随着COVID-19的爆发,人们越来越需要可访问的诊断工具.
- 完整血清 (CBC) 提供了一种具有成本效益的患者评估方法.
- CBC参数对于监测住院患者和预测预后至关重要.
研究的目的:
- 为了评估COVID-19患者中CBC参数的预后值.
- 为了确定特定的CBC指数是否与疾病严重程度和患者的结果相关.
- 评估CBC对住院COVID-19病例的日常随访的实用性.
主要方法:
- 在10天内对100名COVID-19患者进行CBC测试的前性监测.
- 一般病房和重症监护室 (ICU) 患者之间的CBC结果的比较.
- 在入院时计算中性粒细胞与淋巴细胞的比率 (NLR) 和血小板与淋巴细胞的比率 (PLR).
主要成果:
- 强症监护室患者的白细胞 (WBC) 数量显著降低 (P=0.008).
- 与幸存者相比,已故患者的淋巴细胞百分比较低 (P=0.041) 和中性粒细胞百分比较高 (P=0.012).
- 幸存者显示的单细胞百分比明显高 (P=0.003) 比非幸存者.
结论:
- 较低的白血球,淋巴细胞和单细胞百分比,再加上较高的中性粒细胞百分比,表明中度至重度COVID-19的预后不佳.
- CBC参数作为预测COVID-19结果的有价值指标.
- 常规的CBC检测可以帮助管理和选COVID-19患者.
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