在过敏的背景下,探索以加多为基础的对比介质用于逆行色谱
Firaas A Khan1, Joseph Balbona2, David J Hernandez2
1Morsani College of Medicine, University of South Florida, Tampa, USA.
Cureus
|November 29, 2023
概括
对于对有的对比剂过敏的患者来说,稀释的gadobenate dimeglumine为逆行色素学提供了一个安全的替代方案. 这种MRI对比剂成功实现了尿路支架放置的成像,没有任何不良反应.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 过敏和免疫学 过敏和免疫学
背景情况:
- 质对比介质 (ICM) 是非血管性泌尿成像的标准,但可能导致罕见的严重过敏反应.
- 记录有过敏的患者需要替代成像剂以减轻过敏反应风险.
研究的目的:
- 评估基于加多的对比剂的疗效和安全性,作为ICM的替代品,用于逆行色谱.
- 为了证明在有记录的过敏的患者中,尿道手术是一种可行的选择.
主要方法:
- 一名66岁的女性患有已知的过敏症,接受了逆行性皮叶扫描,以治疗尿道结石.
- 一种稀释的溶液 (50:50盐液) 的gadobenate dimeglumine,一个MRI对比剂,被用于模糊化.
- 该程序是在尿路支架放置之前进行的,并在尿路透镜检查期间一个月后重复一次.
主要成果:
- 稀释的gadobenate dimeglumine提供了足够的模糊,以成功地进行逆行色素学和尿路支架的放置.
- 在这两种手术中,患者没有出现任何不良反应.
- 在这个高风险患者中,替代性对比剂被证明是有效和安全的.
结论:
- 稀释的 gadobenate dimeglumine 是一个可行的和有效的替代ICM的逆行色素学在患有过敏的患者.
- 在尿道成像中,当ICM是禁忌时,GBCA可以减轻过敏反应的风险.
- 需要进一步的研究来确定GBCA在泌尿干预中的更广泛的疗效和安全性.
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