在临床牙科中与纳米技术相关的危险
Farheen Tafti1, Suyog Savant2, Tanvi Saraf1
1Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed-to-Be University) Dental College and Hospital, Navi Mumbai, IND.
Cureus
|November 29, 2023
概括
纳米技术提供了先进的牙科材料,但纳米材料对健康的潜在风险需要仔细评估. 需要对纳米粒子毒性和牙科工作场所安全进行更多的研究.
科学领域:
- 牙科材料科学 牙科材料科学
- 纳米技术在医疗保健中的应用.
- 纳米材料的毒理学
背景情况:
- 纳米技术通过新型纳米材料和用于增强口腔健康的设备来彻底改变牙科.
- 纳米材料具有独特的原子/分子特性,使其能够开发出优质的牙科材料.
- 日常牙科应用中纳米材料的使用增加,引发了人们对潜在的无意的生物反应的担忧.
研究的目的:
- 审查牙科中使用的各种纳米材料的毒性.
- 评估纳米颗粒对口腔健康参数和生物障碍的影响.
- 确定纳米牙科安全评估中的知识缺口.
主要方法:
- 关于细胞毒性,基因毒性和纳米粒子相互作用的文献综述.
- 分析纳米粒子通过口腔和胃肠道粘膜的通道.
- 检查纳米粒子对唾液分泌和牙表面微环境的影响.
主要成果:
- 纳米材料,包括复合材料,碳纳米粒子,银纳米粒子 (SNP) 和量子点,表现出不同的毒性.
- 纳米粒子可以通过生理障碍,因为它们的小尺寸.
- 关于牙科材料中纳米颗粒释放的化学物质及其长期影响的数据有限.
结论:
- 纳米牙科提出了有前途的进展,但需要彻底的毒性评估.
- 纳米牙科的潜在好处必须与已确定的风险进行权衡.
- 进一步的研究至关重要,特别是在工作场所暴露在牙科环境中的纳米颗粒.
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