COVID-19和呼吸系统衰竭:来自中西部农村医院的一项回顾性观察研究
Alex Kneller1, Cyril Abadir1, Osaheni Amadasu1
1Medicine, Kansas City University, Joplin, USA.
Cureus
|November 29, 2023
概括
患有COVID-19和呼吸衰竭的患者的死亡率与仅患有呼吸衰竭的患者相似. 患有这两种疾病的老年人 (65岁以上) 面临更高的死亡率,这表明年龄是一个重要的风险因素.
科学领域:
- 临界护理医学 临界护理医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 导致COVID-19,经常出现呼吸系统症状.
- 呼吸衰竭可以模仿或是COVID-19的结果,需要对它们的相互作用进行研究.
- 了解死亡率差异对于改善呼吸道疾病患者的治疗结果至关重要.
研究的目的:
- 为了比较COVID-19入院患者的死亡率,呼吸衰竭或两者兼而有之.
- 分析年龄对这些患者群体死亡率的影响.
主要方法:
- 从2020年4月到2021年12月,对电子病历进行了回顾性分析.
- 包括所有被诊断为COVID-19或呼吸衰竭 (ICD-10代码) 的患者.
- 根据年龄分层的不同患者队伍的死亡率的比较.
主要成果:
- 患有COVID-19和呼吸衰竭的患者与仅患有COVID-19的患者相比,死亡率显著增加 (17.28%).
- 在COVID-19和呼吸衰竭患者与没有COVID-19的呼吸衰竭患者之间没有观察到显著的死亡率差异.
- 65岁及以上的COVID-19和呼吸衰竭患者的死亡率明显高于患有相同疾病的年轻患者.
结论:
- 呼吸衰竭,而不是仅仅是COVID-19,似乎是这两种疾病患者死亡的主要驱动因素.
- 年龄是一个显著的风险因素,老年人 (65岁以上) 在同时被诊断为COVID-19和呼吸衰竭时,死亡率增加.
- 未来的研究应该专注于针对COVID-19和呼吸衰竭的高风险老年人群的量身定制治疗策略.
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