异位甲状腺内甲状腺腺瘤呈现与骨质疏松性骨折在一个年轻人:一个案例报告
Inês Cosme1, Ema Nobre1, André Travessa2
1Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário Lisboa Norte, Lisboa, PRT.
Cureus
|November 29, 2023
概括
初级甲状腺功能障碍症 (PHPT) 即使在年轻男性中也会导致骨质疏松症和骨折. 早期诊断和治疗对于预防骨折和结石等并发症至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
- 手术病理学手术病理学
背景情况:
- 初级副甲状腺症 (PHPT) 与骨质疏松症 (OP) 和骨折有关.
- 异位副甲状腺瘤很少见,甲状腺内部位占病例的0.7%-6%.
- 在这种情况下,脚损伤可能是棕色瘤,表明早期的PHPT.
研究的目的:
- 介绍一个年轻男性的病例,患有复发性骨质疏松性骨折和由于甲状腺内甲状腺腺瘤引起的脏结肠.
- 强调考虑年轻男性骨质疏松症的次要原因的重要性.
- 强调早期诊断和预防PHPT相关发病率的潜力.
主要方法:
- 一个49岁的男性病例报告,有骨折和结的病史.
- 诊断工作包括实验室测试代谢,宫超声波,副甲状腺扫描和双能X射线吸收计 (DXA).
- 手术干预 (甲状腺切除术) 和切除的病变和副甲状腺组织的组织学检查.
主要成果:
- 实验室发现证实了PHPT.
- DXA扫描显示了严重的骨质疏松症 (大腿部部Z-score为-4.3).
- 组织学证实了甲状腺内甲状腺腺瘤和足部结节与棕色瘤一致.
结论:
- 甲状腺内甲状腺腺瘤是PHPT的罕见原因.
- 在这种情况下,PHPT的延迟诊断导致了显著的发病率,包括多重骨折和.
- 年轻男性的骨质疏松性骨折需要对PHPT等次要原因进行调查.
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