新诊断的2型糖尿病患者的心脏自主神经病变
Md Sabah Siddiqui1, Vishnu Dev1, Ekta Khandelwal2
1General Medicine, All India Institute of Medical Sciences, Raipur, Raipur, IND.
Cureus
|November 29, 2023
概括
新诊断的2型糖尿病患者通过异常心率变化和自主功能测试显示心脏自主神经病变 (CAN) 的早期迹象. 早期发现糖尿病CAN对于预防严重并发症至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
背景情况:
- 心脏自主神经病变 (CAN) 是一种严重的糖尿病并发症,影响心脏功能,增加心律失常风险.
- 早期发现和治疗CAN对于改善患者的治疗结果至关重要.
- 这项研究重点关注印度中部新诊断的2型糖尿病患者的CAN患病率.
研究的目的:
- 为了调查心脏自主神经病变 (CAN) 在新诊断的2型糖尿病患者中的患病率.
- 为了比较糖尿病患者和健康对照组之间的自主功能.
- 强调早期CAN诊断在糖尿病管理中的重要性.
主要方法:
- 一项病例控制研究,涉及35名新诊断的2型糖尿病患者和35名年龄相匹配的健康对照.
- 用心率变化 (HRV),深呼吸测试 (DBT),冷压测试 (CPT) 和躺到站测试 (LST) 来评估心脏自主功能.
- 对记录的参数进行了统计分析,以比较组.
主要成果:
- 与对照组相比,2型糖尿病患者的体重,BMI,血糖水平,白蛋白-肌素比率和血压都较高.
- 在DBT和CPT期间HRV和E:I比率的异常在糖尿病患者中更为频繁.
- 在糖尿病组中观察到副交感功能障碍和更高的正静态症状的可能性.
结论:
- 自主功能测试 (AFT) 对于在新诊断的糖尿病患者中诊断早期心脏自主神经病变 (CAN) 至关重要.
- 对糖尿病CAN的及时诊断和干预对于减轻严重并发症至关重要.
- 这项研究强调了在管理2型糖尿病时需要常规的AFT.
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