循环血液中的淋巴细胞和急性胰腺炎的严重程度:系统性审查
Filipa Malheiro1, Margarida L Nascimento2, Ana Carmo1
1Internal Medicine, Hospital da Luz Lisboa, Lisboa, PRT.
Cureus
|November 29, 2023
概括
周围血液淋巴细胞与急性胰腺炎的严重程度有关,急性胰腺炎是一种炎症性胰腺疾病. 本综述阐明了淋巴细胞水平与急性胰腺炎结局之间的关联.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 急性胰腺炎是一种严重的胰腺炎,严重程度的决定因素尚不清楚.
- 了解影响急性胰腺炎进展的因素至关重要.
研究的目的:
- 调查循环淋巴细胞和急性胰腺炎严重程度之间的关联.
- 综合当前关于淋巴细胞在胰腺炎中的作用的证据.
主要方法:
- 在主要数据库 (Medline, Web of Science, Cochrane, ClinicalTrials.gov) 进行系统的文献搜索.
- 根据PRISMA-P指南进行独立的数据选择和提取.
- 纳入和排除标准适用于27783项初步研究,导致13项纳入研究.
主要成果:
- 跨研究的一致发现表明,外周血液淋巴细胞与急性胰腺炎严重程度之间存在关联.
- 周围淋巴细胞水平可以作为胰腺炎结果的生物标志物.
结论:
- 循环的淋巴细胞与急性胰腺炎的严重程度有关.
- 需要进一步的研究来阐明精确的机制,将淋巴细胞与胰腺炎的严重程度联系起来.
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