重症COVID-19患者间隔膜厚度下降的评估:计算机断层扫描对隔膜肌肉质量有帮助吗?
Oana-Elena Branea1,2, Sanda Maria Copotoiu1, Diana Andreea Becica2
1Discipline of Anesthesia and Intensive Care, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, ROU.
Cureus
|November 29, 2023
概括
通过CT扫描测量COVID-19患者的隔膜厚度减少,表明预后不佳. 这一发现突出了CT作为预测机械通风患者的结果的潜在工具.
科学领域:
- 关键护理医学 关键护理医学
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
背景情况:
- 隔膜对于呼吸功能至关重要.
- 有限的研究存在于使用CT的COVID-19患者的隔膜厚度变化.
- 在严重的COVID-19中调查隔膜变化具有临床意义.
研究的目的:
- 为了研究重症COVID-19患者腹膜肌肉厚度的动态变化.
- 评估隔膜厚度变化与临床结果之间的关联.
- 探索胸部计算机断层扫描 (CT) 在评估隔膜变化的实用性.
主要方法:
- 在第三级重症监护病房 (ICU) 进行了回顾性观察性研究.
- 包括患有严重COVID-19的成年患者接受两次胸部CT扫描.
- 测量腹膜厚度在腹膜干部水平.
主要成果:
- 观察到隔膜厚度的显著平均减少: -0.58毫米 (右) 和 -0.54毫米 (左).
- 在CT扫描中,隔膜厚度在两侧显著下降 (p=0.02).
- 发现了负相关性;右 (> -0.175) 和左 (> -0.435) 隔膜的特定切断值表明预后不佳,机械通风持续时间长,ICU死亡风险增加.
结论:
- 隔膜的胸部CT评估是一个潜在的可靠工具.
- 这种方法可以帮助预测机械通风COVID-19患者的肌肉修饰.
- 隔膜厚度的变化与严重的COVID-19中不良的临床结果相关.
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