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Updated: Jul 9, 2025

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在类风湿性关节炎中,RhoA通过Wnt/PCP通路促进突增殖和骨侵蚀

Ning Chen1,2, Chao-Yue Diao1, Xin Huang3

  • 1Department of Rheumatology and Immunology, Changhai Hospital, Naval Medical University, Shanghai, China.

Mediators of inflammation
|November 29, 2023
PubMed
概括

拉斯同源基因家族成员A (RhoA) 在类风湿性关节炎 (RA) 中过度表达. 沉默RhoA在小鼠模型中减少了RA纤维细胞样同胞细胞入侵和骨质侵蚀,这表明RhoA是一个治疗目标.

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