异胎妊娠病例中破裂的患病率和相关因素;系统性审查和元分析
Chenchen Xu1, Zhilei Mao1, Mi Tan1
1Department of gynecology and obstetrics, Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, 213000 China.
Archives of academic emergency medicine
|November 29, 2023
概括
异胎妊娠 (EP) 破裂影响了超过一半的病例,许多因素影响了其发生. 早期查和解决可修改的风险因素对于管理EP破裂和改善患者结果至关重要.
科学领域:
- 生殖健康 生殖健康
- 妇科 妇科医生 妇科
- 产科 产科 产科 产科 产科
背景情况:
- 宫外怀孕 (EP) 带来重大风险,包括出血,手术并发症和产妇死亡率,特别是当诊断和治疗延迟时.
- 在EP病例中,破裂是关键事件,需要对其流行率和相关风险因素进行彻底了解.
研究的目的:
- 为了确定子宫外妊娠 (EP) 病例中破裂的综合流行率.
- 为了确定与EP中断裂的流行率相关的因素.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,Iranmedex,科学信息数据库) 进行了系统的文献搜索,直到2022年12月.
- 使用CMA程序进行了元分析,计算了整体效应大小,并用I2统计数据测量异质性.
主要成果:
- 这项研究分析了17项涉及5269名EP妇女的研究.
- 发现EP断裂的综合流行率为56.4% (95% CI: 44.9%至67.2%).
- 许多因素,包括患者人口统计学,荷尔蒙水平,怀孕特征和临床症状,与EP破裂有关.
结论:
- 超过一半的异位妊娠病例导致破裂,突出强调及时干预的紧迫性.
- 对医疗保健提供者和政策制定者来说,识别和管理可修改的风险因素对于降低EP破裂率和改善孕产妇结果至关重要.
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