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纳米技术为草药和植物制药提供药物的当前进展
Amir Jalili1, Rafieh Bagherifar2,3, Ali Nokhodchi4,5
1Department of Pharmaceutical Technology, Faculty of Pharmacy, Eastern Mediterranean University, Famagusta, North Cyprus.
Advanced pharmaceutical bulletin
|November 29, 2023
概括
纳米技术通过提高溶解度和生物可用性来增强传统草药. 本综述探讨了纳米载体系统,以提高植物药物的治疗疗效.
科学领域:
- 药理学 药理学是指药理学的学科.
- 材料科学 材料科学 材料科学
- 药物运输 药物运输 药物运输
背景情况:
- 植物医药提供了历史性的治疗益处,但由于溶解性差,不稳定性和低生物可用性而受到影响.
- 这些局限性阻碍了许多传统草药疗法的临床疗效.
- 克服这些挑战对于实现草药的全部潜力至关重要.
研究的目的:
- 审查纳米技术的应用,以克服草药的配方挑战.
- 总结各种基于纳米的植物药物药物输送系统.
- 讨论纳米植物药的制备技术和临床进展.
主要方法:
- 科学数据库和临床试验注册表的文献综述.
- 对纳米载体系统用于草药药物输送的研究进行分析.
- 在临床试验和FDA批准中对纳米植物药物的数据的汇编.
主要成果:
- 基于纳米技术的系统有效地解决了草药化合物的可溶性差和不稳定性.
- 包括纳米颗粒,脂质体和纳米乳液在内的各种纳米载体显示出增强传递的前景.
- 几种纳米植物药物已经进入临床试验,并获得了监管机构的关注.
结论:
- 纳米技术提供了一种可行的策略,以提高植物药物的生物可用性和治疗疗效.
- 纳米植物药物的开发正在推进,具有有前途的临床结果.
- 纳米配送系统的进一步研究和开发可以为草药开发新的治疗应用.
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