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Updated: Jul 9, 2025

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使用基于结构的虚拟查,分子动态模拟和生物评估发现强大的STAT3抑制剂

Weifeng Liu1, Zhijie Chu1, Cheng Yang1

  • 1Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan, China.

Frontiers in oncology
|November 29, 2023
PubMed
概括

这项研究通过准信号传感器和转录3激活器 (STAT3) 来确定化合物4是胃癌的强有力的抑制剂. 化合物4在减少癌细胞增殖和线粒体功能方面表现出有效性.

关键词:
在STAT3中,我们可以使用STAT3.胃癌 胃癌 是一种胃癌.分子对接的分子对接.分子动态模拟分子动态模拟基于结构的虚拟选.

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