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Updated: Jul 2, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
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阿伦德罗纳酸增加了ASC缺陷RAW264细胞通过AP-1激活的脂质A诱导的IL-1β释放

Noriyuki Watanabe1, Riyoko Tamai1,2, Yusuke Kiyoura1,2

  • 1Department of Oral Infectious Diseases, Ohu University Graduate School of Dentistry, Koriyama, Fukushima 963-8611, Japan.

Experimental and therapeutic medicine
|November 29, 2023
PubMed
概括

阿伦德罗纳酸 (ALN) 通过增加互白素-1β (IL-1β) 释放来增强对脂质A的炎症反应. 这通过激活蛋白1 (AP-1) 的激活发生,而不是NF-κB,导致细胞损伤.

关键词:
激活蛋白1 激活蛋白1 激活蛋白1阿伦德罗纳酸盐是什么意思与亡相关的斑状蛋白质含有caspase招募域.介质素-1ββ的使用.含有的双酸含有.

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Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice07:36

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...