在患有清细胞脏细胞癌的患者中感染细胞巨病毒
Ikhwan Rinaldi1, Abdul Muthalib1, Januar Widodo Sutandar2
1Division of Hematology and Medical Oncology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Case reports in medicine
|November 29, 2023
概括
细胞巨乳病毒 (CMV) 感染可以在免疫功能低下的癌症患者中引起严重疾病. 本案例报告详细介绍了一名接受向疗法治疗的癌患者,该患者经历了CMV再激活,并用甘西克洛维尔成功治疗.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 细胞巨乳病毒 (CMV) 感染是常见的,但在免疫功能低下的个体,包括癌症患者,可能是严重的.
- 关于癌患者中CMV感染的文献有限,特别是那些接受向治疗的人.
- 癌症治疗可以增加机会性感染的风险,如CMV.
研究的目的:
- 在接受向治疗的癌患者中报告细胞巨乳病毒 (CMV) 感染再激活的病例.
- 突出在这个脆弱的患者群体中识别和管理CMV感染的重要性.
主要方法:
- 本文介绍了一个61岁男性患有清细胞细胞癌的病例报告.
- 该患者接受了伦瓦替尼 (一种受体激酶激酶抑制剂) 和埃弗罗利斯 (一种哺乳动物的拉巴胺抑制剂标) 的向治疗.
- 通过聚合酶链反应 (PCR) 证实了CMV感染的诊断,治疗包括甘西克洛维尔,其次是瓦尔甘西克洛维尔.
主要成果:
- 该患者出现呼吸困难,并被诊断为CMV感染的重新激活.
- 用甘西克洛维尔治疗导致症状显著改善,包括呼吸短促,咳和发烧.
- 随后的维护治疗中,瓦尔甘克洛维尔的耐受性很好,在进一步治疗癌症期间没有复发.
结论:
- 细胞巨乳病毒 (CMV) 感染的重新激活是接受向治疗的癌患者的潜在并发症.
- 及时诊断和使用甘西克洛维尔等抗病毒药物的治疗对于这些患者的CMV感染管理至关重要.
- 对于管理癌症患者的医疗保健专业人员来说,对CMV感染风险的认识至关重要,特别是在高患病率地区.
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