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Updated: Aug 12, 2026

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m6 一个表皮转录组分析揭示了差异甲基化转录,驱动膀癌早期化学抵抗

Emmanuelle Hodara1, Aubree Mades1, Lisa Swartz1

  • 1Division of Medical Oncology, Department of Medicine, Keck School of Medicine of USC and Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.

NAR cancer
|November 29, 2023
PubMed
概括

在膀癌中,N-Methyladenosine (m6A) RNA的修改通过上调SLC7A11.11来驱动化学抵抗. 这种表体转录性可塑性为克服抗药性提供了潜在的治疗点.

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