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免疫接种后的不良事件 (AEFI):印度尼西亚中央爪的COVID-19疫苗剂量和特征

Firdaus Wahyudi¹, Arwinda Nugraheni², Ani Margawati³

¹MD, OB/GYN, Public Health and Preventive Medicine, Department of Medicine, Faculty of Medicine, Diponegoro University, Semarang, Indonesia, 50275, Tembalang district, Semarang city, Indonesia.

|November 29, 2023

概括

针对COVID-19疫苗的免疫接种后不良事件 (AEFI) 根据剂量而异. 年龄,性别和之前的COVID-19感染等因素影响了AEFI风险,突出了个性化监测策略的必要性.

科学领域:

公共卫生公共卫生
流行病学流行病学
疫苗学疫苗学疫苗学

背景情况:

由于COVID-19的流行,疫苗接种工作变得更加必要.
疫苗虽然有效,但可以导致免疫接种后的不良事件 (AEFI).
在研究期间,印度尼西亚接种了几种COVID-19疫苗.

研究的目的:

分析与COVID-19疫苗AEFI相关的因素.
为了检查AEFI在社区中使用的每一剂疫苗.
在不同疫苗接种阶段识别AEFI的特定风险因素.

主要方法:

横截面研究设计. 截面研究设计.
在印度尼西亚中央爪省进行 (2021年8月至10月).
通过问卷收集的数据,使用后勤回归分析.

主要成果:

AEFI率为21.1% (第一剂量),14.1% (第二剂量) 和83.9% (第三剂量).
与AEFI相关的因素因剂量而异:年龄>45岁和超重 (第一剂量);超重,女性性别,年龄>45岁和COVID-19之前 (第二剂量);女性性别 (第三剂量).
对于每个相关因素和剂量,确定了特定的几率比率和置信区间.

结论:

COVID-19疫苗AEFI的相关因素包括性别,年龄,营养状况和之前的COVID-19病史.
对AEFI的危险因素是剂量依赖的.
这些发现强调了在疫苗安全监测中考虑个体特征的重要性.

关键词:

一个AEFI的AEFI.这是COVID-19疫苗.它们的特性,特点.剂量剂量剂量剂量剂量

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