冠状病毒疾病2019和肺癌:我们在哪里?
Abrahams Ocanto1,2, Xabier Mielgo-Rubio3, Javier Luna Tirado4
1Department of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesiCare Madrid, 28002 Madrid, Spain.
Exploration of targeted anti-tumor therapy
|November 29, 2023
概括
瘤学患者面临严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 的更高风险. 疫苗接种显著降低了这些癌症患者的死亡率,显示出积极的影响.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 瘤学患者因医院暴露和癌症治疗免疫力受损而增加了对SARS-CoV-2的敏感性.
- COVID-19和肺癌 (LC) 病理生理学的相似性导致癌症患者更严重的疾病,更高的住院率和癌症患者的死亡率.
- 吸烟,并发性疾病,年龄较大和皮质类固醇使用等危险因素加剧了瘤病患者的COVID-19严重程度.
研究的目的:
- 突出瘤学患者在SARS-CoV-2感染方面所面临的独特挑战.
- 强调像COVID-19报告和数据系统 (CO-RADS) 这样的诊断工具的重要性,以准确诊断肺癌患者.
- 讨论癌症治疗中的适应性和疫苗接种对这一弱势群体的影响.
主要方法:
- 对瘤病患者的SARS-CoV-2感染现有文献的综述.
- 对癌症疗法和伴随性疾病对COVID-19结果的影响分析.
- 在大流行背景下对诊断尺度 (CO-RADS) 和治疗修改的评估.
主要成果:
- 预先存在的肺部疾病和癌症治疗改变了肺部结构,使得准确的诊断至关重要.
- 实施了抗癌治疗适应措施,如低分离放射治疗和延迟化疗,以减少医院访问.
- 癌症治疗的修改无意中导致了新癌症的诊断延迟.
- 疫苗接种对瘤患者的死亡率产生了积极的影响,血清流行率与一般人群相似.
结论:
- 瘤学患者需要特别考虑SARS-CoV-2管理,因为他们的脆弱性增加.
- 诊断工具和适应的治疗策略对于癌症患者的COVID-19管理至关重要.
- 疫苗接种是一个关键的干预措施,成功降低了这一高风险群体的死亡率.
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