范围相关出版物和临床试验的时间趋势:一个图书统计审查
Pranav M Patel1, Richard M Abaniel1, Natasha Dogra2
1Abbott Diabetes Care, Alameda, CA.
Diabetes spectrum : a publication of the American Diabetes Association
|November 29, 2023
概括
关于血糖时间范围 (TIR) 的出版物和临床试验激增,特别是在2018年以来. 这一趋势强调了TIR.
科学领域:
- 糖尿病管理 糖尿病管理
- 临床研究趋势
- 血糖控制指标 血糖控制指标
背景情况:
- 时间范围 (TIR) 是评估糖尿病血糖控制的越来越重要的指标.
- 了解TIR的出版和临床试验环境对于跟踪研究进展至关重要.
研究的目的:
- 描述出版物和临床试验中的趋势,报告从2010年到2021年的血糖时间范围 (TIR).
- 分析研究的增长和特点,以TIR作为结果衡量标准.
主要方法:
- 系统审查报告TIR的出版物和临床试验,来源于MEDLINE和Embase等数据库.
- 纳入标准侧重于2010年至2021年间发表或启动的英语研究,不包括非人类和无关研究.
- 数据提取包括出版年,研究地区,使用持续血糖监测 (CGM) 和报告的血糖结局 (TIR,A1C,TBR,TAR).
主要成果:
- 报告TIR的出版物,摘要和临床试验显著增加,特别是在2018年至2021年之间 (分别增加了6倍,12倍和4.5倍).
- 在35-44%的研究中,TIR被报告为主要结果.
- 持续血糖监测 (CGM) 主要是观察性的 (47-54%的研究),并且在范围以下的时间 (TBR) 比在范围以上的时间 (TAR) 更频繁地报告.
结论:
- 与TIR相关的研究大幅增长表明其在糖尿病管理中的重要性和接受度日益增加.
- 这一趋势凸显了临床实践和研究中血糖结果测量的不断变化的格局.
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