常规实验室参数,以支持在息护理中对腹腔营养的决定
Lea Kum1, Elisabeth L Zeilinger1,2,3, Dagmar Vohla1
1Division of Palliative Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Frontiers in nutrition
|November 29, 2023
概括
亲肠道营养 (PN) 在生命末期 (EOL) 的使用可以通过实验室标记来指导. 使用CRP,尿素和LDH的决策树模型可以预测存活率,有助于在息护理中PN启动决策.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 临床营养学 临床营养学
- 生物统计学 生物统计学
背景情况:
- 亲肠道营养 (PN) 在息护理 (PC) 中很常见,但缺乏强有力的生命终结 (EOL) 证据.
- 在EOL中关于PN的临床决定需要更好的证据.
研究的目的:
- 研究接受PN的患者常规实验室参数和生存率之间的联系.
- 开发一个预测模型,以指导在EOL护理中的PN启动决策.
主要方法:
- 在113名晚期疾病患者中分析了实验室参数 (T0:PN前,T1:PN后2周).
- 采用曼-惠特尼U测试,线性回归和决策树分析.
- 与PN启动后的生存时间相关联的实验室值.
主要成果:
- 回归模型将CRP/白蛋白比率和T1的尿素确定为显著的生存预测因子 (p=0.001).
- 决策树分析强调了CRP,尿素和LDH在T0时作为生存分类的关键预测因素.
结论:
- 使用基线CRP,尿素和LDH的决策树模型可以帮助临床医生识别可能受益于PN的患者.
- 该模型支持在息护理环境中关于启动或保留PN的知情决定.
关键词:
生物标志物 生物标志物卡赫西亚 (Cachexia) 是一种缓解症.癌症 癌症 癌症 癌症 癌症决策树是一个决策树.抚慰性护理是一种缓解性护理.亲肠营养 亲肠营养预测得分 预测得分常规的实验室参数更多相关视频
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