质限制在刺激性肠综合征,是还是不是? :一个GRADE评估的系统审查和元分析
Erfan Arabpour1, Dorsa Alijanzadeh1, Amir Sadeghi1
1Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Frontiers in nutrition
|November 29, 2023
概括
与含有质的饮食相比,无质饮食 (GFD) 并不能显著降低刺激性肠综合征 (IBS) 的症状. 低发酵性橄糖,二糖,单糖和多醇饮食 (LFD) 在IBS症状管理中表现出更大的有效性.
科学领域:
- 胃肠病学 胃肠病学
- 饮食科学 饮食科学
- 临床营养学 临床营养学
背景情况:
- 刺激性肠综合征 (IBS) 影响了超过一半报告食物触发症状的患者.
- 低发酵性橄糖,二糖,单糖和多醇饮食 (LFD) 是IBS的常见饮食干预措施.
- 关于质限制对IBS症状改善的有效性存在相互矛盾的证据.
研究的目的:
- 评估无质饮食 (GFD) 对刺激性肠综合征 (IBS) 症状的影响.
- 为了比较GFD与含质饮食和LFD在IBS症状管理中的有效性.
主要方法:
- 在主要数据库 (PubMed/Medline,Cochrane CENTRAL,Scopus,Web of Science) 进行系统的文献搜索,截至2023年4月.
- 使用随机效应模型对9项受控试验的元分析.
- 标准化平均差异 (SMD) 和95%置信区间 (95%CI) 为各种结果计算.
主要成果:
- 与含质饮食相比,GFD没有显著减少整体IBS症状,胀气或改善生活质量.
- 与GFD (SMD -0.68;95% CI -1.36, -0.00) 观察到减少腹痛的趋势.
- 与GFD相比,LFD显著降低了IBS严重性评分系统 (SMD 0.66;95%CI 0.31,1.01) 和改善了生活质量 (SMD -0.36;95%CI -0.70, -0.01).
结论:
- 对于IBS患者的常规推,GFD没有足够的稳定性.
- 在控制IBS症状方面,GFD的疗效明显低于LFD.
- 需要进一步的研究来确定可能受益于GFD的特定IBS子组.
相关概念视频
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