与原相关的piRNA的表达在从硬化皮肤病患者获得的培养皮肤纤维细胞中失调

Minako Tanaka1, Yutaka Inaba1, Azusa Yariyama1

  • 1Department of Dermatology, Wakayama Medical University, Wakayama, Japan.

PubMed
概括

系统性硬化症 (SSc) 涉及异常的原蛋白. 研究人员发现piR-32364,一种PIWI相互作用RNA (piRNA),在SSc纤维细胞中被上调,并可能调节原蛋白的产生,这表明piRNAs是潜在的治疗标.

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