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0至35个月龄的儿童用蛋,牛奶或小麦敏感化的Jug r 1敏感化
Katsumasa Kitamura1, Teruaki Matsui1, Yoshihiro Takasato1
1Aichi Children's Health and Medical Center, Allergy and Immunology Center, Obu, Japan.
The journal of allergy and clinical immunology. Global
|November 29, 2023
概括
儿童对核桃过敏的情况正在上升. 一项研究发现,15%的幼儿患有湿疹并对蛋,牛奶或小麦敏感,也对核桃敏感 (Jug r 1).
科学领域:
- 儿科过敏和免疫学
- 临床免疫学临床免疫学
- 皮肤病学 皮肤病学
背景情况:
- 儿童树核过敏症,特别是核桃过敏症,在全球范围内正在增加.
- 对树木坚果的早期过敏反应表明了先前的敏感性.
- 识别有敏感性风险的儿童对于早期干预至关重要.
研究的目的:
- 为了确定哪些孩子应该被评估是否已经存在对核桃的敏感性.
- 调查核桃 (Juglans regia) 1 特定IgE在其他食物过敏的幼儿中的流行情况.
主要方法:
- 对205名年龄在0-35个月的儿童进行了回顾性分析,这些儿童对蛋,牛奶或小麦呈阳性IgE.
- 在从未吃过核桃的儿童中查Juglans regia (Jugr) 1特定IgE.核桃.
- Jugr 1敏感度与湿疹严重程度以及对其他过敏原的敏感度的相关性.
主要成果:
- 测试的儿童中有9.8%为Jugr1特定的IgE呈阳性.
- 在患有湿疹 (15.1%) 的儿童中, Jug r 1 敏感性明显高于没有湿疹的儿童 (2,3%).
- 患有严重湿疹的儿童表现出明显更高的Jugr 1敏感率 (26.6%).
结论:
- 大约有15%的三岁以下儿童患有湿疹,对蛋,牛奶或小麦敏感,对核桃也敏感 (Jug r 1).
- 湿疹是幼儿对核桃共同敏感性的重要危险因素.
- 在高危儿科群体中,建议针对核桃过敏进行有针对性的查.
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