与癌症相关的中风和急性内血管再输液疗法
1Department of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Journal of neuroendovascular therapy
|November 29, 2023
概括
接受内血管治疗 (EVT) 的癌症急性中风患者需要个性化治疗. 虽然结果可能会更差,但EVT并不不合适,需要在癌症相关的中风中共同做出决定.
科学领域:
- 神经学 神经学
- 在瘤学瘤学.
- 血管医学 血管医学
背景情况:
- 卒中经常与癌症有关,其中6-7%的内血管治疗 (EVT) 病例涉及患有活跃癌症的患者.
- 与癌症相关的中风有不同的病因,包括高凝血,瘤栓塞,血管入侵和治疗效应.
- 高凝血诱发的中风涉及诸如悖论性栓塞和非细菌性血栓性内心炎之类的实体.
研究的目的:
- 审查接受EVT的癌症患者急性中风的机制,诊断考虑和治疗策略.
- 分析与非癌症中风患者相比,癌症相关中风患者的EVT结果.
- 突出结血栓在与癌症相关的高凝血能力中的独特特征,以及它们对结血栓切除术的影响.
主要方法:
- 对癌症相关中风的EVT观察研究的综述.
- 对手术前成像和血清生物标志物的分析,用于中风和血栓的特征.
- 对血栓切除术技术和二次预防策略的评估.
主要成果:
- 癌症相关中风的EVT显示了较差的临床结果,但与非癌症中风相比,再输和出血率相似.
- 与癌症相关的高凝血性中的血栓是富含血小板的,难以检索.
- 图像 (例如,高密度血管标志) 和生物标志物 (例如,D-二次元) 有助于评估中风和血栓特征.
结论:
- 与癌症相关的中风是复杂的,需要基于多种机制的个性化治疗.
- 不应该仅仅因为癌症活跃而拒绝 EVT;共享决策至关重要.
- 优化诊断,EVT技术和二次预防是改善这些患者生活质量的关键.
相关概念视频
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