基于平板电脑的认知干预对轻度认知障碍患者的认知的影响:试点研究
Ji Young Park1, Seon Ae Choi1, Jae Joon Kim1
1Geumcheon Center for Dementia, Seoul, Korea.
Dementia and neurocognitive disorders
|November 29, 2023
概括
一个基于平板电脑的认知干预计划在改善轻度认知障碍 (MCI) 患者的认知功能方面显示出可行性和有效性. 这些好处在干预后至少持续了三个月.
科学领域:
- 神经学 神经学
- 老年学是指老年学的学科.
- 数字健康数字健康
背景情况:
- 认知干预措施有望缓解轻度认知障碍 (MCI) 的认知衰退.
- 传统的基于群体的认知计划在临床实践中面临局限性.
- 开发了一种基于平板电脑的新型认知干预来解决这些局限性.
研究的目的:
- 为了研究12周结构化基于平板电脑的认知干预计划的可行性.
- 评估该计划对MCI患者认知功能的影响.
主要方法:
- 一项单臂研究涉及24名被诊断患有MCI的患者.
- 参与者完成了为期12周的基于平板电脑的计划,每周参加5次会议.
- 在基线,干预后和六个月的随访期间,使用联盟建立阿尔茨海默病评估包注册表 (CERAD-K) 的韩国版本评估认知功能.
主要成果:
- 基于平板电脑的计划在MCI患者中实现了83.3%的完成率.
- 干预后观察到CERAD-K总分的显著改善 (p=0.026) 并在三个月后维持 (p=0.004).
- 抑郁症等级得分的改善也被注意到 (p=0.002) 并在三个月内持续 (p=0.027).
结论:
- 基于药片的12周结构化计划对患有MCI的患者来说是可行的.
- 该计划展示了作为预防MCI认知衰退的有效策略的潜力.
- 需要对双臂设计进行进一步的研究来证实有效性.
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