儿童门性高血压:土耳其的三级中心体验
Emine Nur Sunar Yayla1, Sinan Sarı2, Neslihan Gürcan Kaya2
1Department of Pediatrics, Faculty of Medicine, Gazi University, Ankara, Turkey.
Pediatric gastroenterology, hepatology & nutrition
|November 29, 2023
概括
儿童的门脉高血压 (PH) 有多种原因,如门脉血栓形成和胆道缩. 没有肝硬化的PH可能会比患有肝硬化的PH更严重的并发症.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 肝病学 肝病学是一种肝病学.
- 临床研究 临床研究
背景情况:
- 门高血压 (PH) 显著影响儿科的发病率和死亡率.
- 了解儿童PH的范围对于有效管理至关重要.
研究的目的:
- 评估儿科PH的病因学,临床,实验室和内镜发现.
- 分析儿科PH患者的治疗方法,长期结果和预后.
主要方法:
- 在1998年至2016年期间,对222名被诊断患有PH的儿科患者进行了回顾性研究.
- 对临床,实验室,放射学特征,治疗和并发症的分析.
主要成果:
- 常见的原因包括门静脉血栓症 (20.3%),进展性家族性肝内胆固醇症 (18.9%),胆道缩 (12.2%).
- 肝硬化 (59.0%) 和非肝硬化 (41.0%) 组表现出不同的临床特征.
- 非肝硬化PH患者患有更多的水出血,而肝硬化患者患有更多的瘤和肝脏脑病.
结论:
- 肝外门静脉阻塞,遗传代谢性疾病和胆道缩是儿科PH的关键原因.
- 临床迹象,如肝扩大症和高氨酸酶,表明肝硬化PH.
- 没有肝硬化的儿科PH可能表明更严重的病情.
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