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儿童和青少年的功能性胃肠道疾病和腹部内脏脂肪
Chang Yun Kim1, Jae Hyuk Hyun2, Eell Ryoo1
1Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.
Pediatric gastroenterology, hepatology & nutrition
|November 29, 2023
概括
儿童和青少年的功能性胃肠道疾病 (FGID) 与腹部内脏脂肪减少有关,特别是在男孩中. 群体之间的肥胖程度没有差异,但性别影响了FGID和肥胖相关性.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 肥胖问题研究研究
- 医学成像分析 医学成像分析
背景情况:
- 功能性胃肠道疾病 (FGID) 在儿童和青少年中很常见.
- FGIDs与肥胖,特别是内脏脂肪之间的关系需要在儿科患者群体中进一步调查.
研究的目的:
- 研究功能性胃肠道疾病 (FGIDs) 与儿童和青少年肥胖程度之间的相关性.
- 为了确定腹部内脏脂肪在儿科FGID患者和对照人群之间是否有差异.
主要方法:
- 在2015-2016年被诊断患有FGID的儿科患者 (<19岁) 进行了回顾性病例控制研究.
- 用专门的软件分析了腹腔皮层计算机断层扫描,以测量腹部内脏脂肪.
- FGID患者与对照组进行了比较,比率为1:2.
主要成果:
- 在FGID和对照组之间没有发现体重指数 (BMI) 的显著差异 (p=0.150).
- 与对照组相比,FGID组的腹部内脏脂肪显著减少 (p=0.048).
- 与对照男孩相比,患有FGID的男孩的BMI (p=0.019) 和腹部内脏脂肪 (p=0.020) 较低,而在女孩中没有观察到差异.
结论:
- FGIDs和肥胖程度之间的关系因性别而异,这表明性激素在FGID病变发生过程中发挥了作用.
- 需要进一步的多中心研究,以更大的队列来澄清FGID亚型和肥胖水平之间的相关性.
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