末尾呼吸道阻塞试验和迷你液体挑战试验用于预测急性循环衰竭中的液体反应
Velmurugan Selvam1,2, Dilip Shende1, Rahul Kumar Anand1
1Department of Anesthesia, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
Journal of emergencies, trauma, and shock
|November 29, 2023
概括
末尾呼吸阻塞试验 (EEOT) 和迷你液体挑战 (MFC) 准确预测急性循环衰竭患者的液体反应. 这些方法评估左心室外流通道速度时间积分 (LVOT VTI) 的变化,以指导液体的输送.
科学领域:
- 关键护理医学 关键护理医学
- 心血管生理学心血管生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 在急性循环衰竭中预测液体反应对于患者管理至关重要.
- 末尾呼吸阻塞试验 (EEOT) 和迷你流体挑战 (MFC) 是评估流体反应的动态方法.
- 被动腿抬起 (PLR) 是一种流体响应性评估的常用方法.
研究的目的:
- 评估EEOT和MFC对急性循环衰竭中流体反应的预测值.
- 为了比较EEOT和MFC与PLR测试在预测流体响应性的有效性.
主要方法:
- 这项研究涉及100名急性循环衰竭的重症患者,呼吸器和镇静剂患者.
- 测量左心室外流通道速度时间积分 (LVOT VTI) 使用 EEOT 和 MFC 之前和之后的跨胸腔心声学.
- 在EEOT (ΔVTIEEOT) 和MFC (ΔVTIMFC) 之后LVOT VTI (ΔVTI) 的变化计算,以预测流体响应.
主要成果:
- 预测流体反应率为9.1%的ΔVTIMFC截止值,灵敏度为91.5%和特异性为88.9% (AUROC 0.96).
- 4.3%的ΔVTIEEOT截止值预测了流体响应,具有89.4%的灵敏度和88.9%的特异性 (AUROC 0.97).
- 在17名患者中,EEOT是不可行的,原因是呼吸器因呼吸力而触发.
结论:
- 无论是 ΔVTIMFC 和 ΔVTIEEOT 都是急性循环衰竭机械通风患者流体反应的准确预测器.
- 这些动态方法为指导重症患者的流体治疗提供了宝贵的见解.
- 在PLR可能效率较低的情况下,EEOT和MFC为评估流体响应提供了可靠的替代方案.
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