perfusion

Ross M Warner1, Jun Yang1, Andrew Drake1

  • 1School of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, Oregon, United States.

PeerJ
|November 29, 2023
PubMed
概括

器官冷保存使用冷保护剂 (CPA) 防止冰损伤. 这项研究揭示了CPA车辆溶液强度对脏大小和血液流量产生影响,这对于优化冷保存协议至关重要.

相关概念视频

Formation of Dilute Urine01:20

Formation of Dilute Urine

The formation of dilute urine is a critical renal adaptation that maintains fluid balance, particularly during periods of high fluid intake. This process primarily involves the juxtamedullary nephrons. By adjusting the permeability of water and ions in response to physiological conditions, the kidneys can either conserve or excrete water, resulting in concentrated or dilute urine.
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Dialysis01:15

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Regulation of Water Intake01:25

Regulation of Water Intake

Osmolality refers to the number of solute particles per kilogram of solvent in a solution. Plasma osmolality specifically indicates the total number of solute particles per kilogram of water in blood plasma. This value reflects the body's hydration status and is tightly regulated through mechanisms controlling water intake and output. While water consumption is a conscious decision, the body has intrinsic regulatory systems to maintain fluid balance. Dehydration, a state of water deficit...
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Formation of Concentrated Urine01:23

Formation of Concentrated Urine

There is a gradient of solutes in the interstitial fluid from the renal cortex through the medulla, known as the medullary osmotic gradient. The juxtamedullary nephrons establish and maintain this gradient using countercurrent mechanisms with loops extending deep into the medulla. These nephrons also use countercurrent mechanisms to regulate urine volume and concentration. The interaction between the descending and ascending limbs of the nephron loop creates an osmotic gradient through...
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