关于口腔状细胞癌的分子生物学研究的研究趋势:图书识别分析
Indrayadi Gunardi1,2, Irna Sufiawati3, Hanna Goenawan4,5
1Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Oncology reviews
|November 29, 2023
概括
口腔状细胞癌 (OSCC) 的分子生物学研究正在迅速扩大. 关键主题包括表皮生长因子受体和表皮-介质酶过渡,未来的重点是化学抵抗和炎症,以改善口腔癌的检测和治疗.
科学领域:
- 分子生物学分子生物学
- 在瘤学瘤学.
- 生物技术是生物技术.
背景情况:
- 自PCR和ELISA出现以来,口腔状细胞癌 (OSCC) 的体外分子生物学研究显著扩大.
- 口腔状细胞癌 (OSCC) 研究已经发展,需要对其分子景观进行全面的概述.
研究的目的:
- 提供关于口腔状细胞癌 (OSCC) 的分子生物学研究的全面概述.
- 利用视觉绘图技术来分析OSCC分子生物学研究中的趋势和关键领域.
主要方法:
- 从Scopus核心集合 (1992-2023) 中分析了781篇出版物,使用关键词"口腔状细胞癌"和"细胞系".
- 使用Microsoft Excel 2010和VOSviewer进行数据分析,以查找作者,期刊,机构和国家贡献.
- 使用VOSviewer进行关键词的并发和参考分析,以确定中心主题.
主要成果:
- 日本,中国和美国是主要的贡献者;大阪大学牙科研究生院和Chae J-I的生产力很高.
- 国际瘤学杂志和口腔病理学和医学杂志是最多产的期刊.
- 关键的研究主题包括表皮生长因子受体,侵袭,表皮-介质细胞过渡,血管生成,亡和转移.
结论:
- 在OSCC分子生物学研究的出版率显著增加.
- 研究重点已经转向化学抵抗,自,炎症,microRNA,癌症相关纤维细胞和STAT3.
- 这些新兴领域有望确定可靠的生物标志物,用于口腔癌的检测,治疗和改善临床结果.
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