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Updated: Jul 9, 2025

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在液体抗溶剂结晶和随后的冷干燥过程中,添加剂对药物颗粒的影响

Peuli Ghosh1, Ake Rasmuson1,2, Sarah P Hudson1

  • 1SSPC, the Science Foundation Ireland Research Centre for Pharmaceuticals, Department of Chemical Sciences, Bernal Institute, University of Limerick, Limerick V94 T9PX, Ireland.

Organic process research & development
|November 29, 2023
PubMed
概括

多种添加剂在抗溶剂结晶和冷干燥过程中稳定了纤维酸和达尔塞特拉皮的纳米颗粒. 虽然多种添加剂最初产生较小的颗粒,但所有配方在干燥后都显示出类似的溶解概况.

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