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O-GlcNAcylation 调节了 OTX2 的蛋白质稳定

Eugenia Wulff-Fuentes1, Jeffrey Boakye2, Kaeley Kroenke1

  • 1Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

iScience
|November 29, 2023
PubMed
概括

O-GlcNAcylation 增强了OTX2蛋白质的溶解性,防止了有害的聚合. 这种翻译后的修改对大脑发育至关重要,对治疗大脑疾病和癌症有影响.

关键词:
生物化学 生物化学癌症 癌症 癌症 癌症细胞生物学 细胞生物学蛋白质组学是指蛋白质组学.

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