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Updated: Jul 9, 2025

New Tools to Expand Regulatory T Cells from HIV-1-infected Individuals
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New Tools to Expand Regulatory T Cells from HIV-1-infected Individuals

Published on: May 30, 2013

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活体GITR激活ex vivo会损害HIV感染者接受抗逆转录病毒疗法的CD8T细胞功能

Céline Gubser1, Rachel D Pascoe2, Judy Chang1

  • 1Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.

iScience
|November 29, 2023
PubMed
概括

葡萄糖皮质醇诱导的瘤亡因子相关蛋白 (GITR) 激活会损害抗逆转录病毒疗法 (ART) 治疗艾滋病毒感染者 (PWH) 的艾滋病毒免疫反应. 由于这些发现,GITR激活剂不建议用于艾滋病毒治愈策略.

关键词:
细胞生物学 细胞生物学免疫学 免疫学 免疫学

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