围产期结核病 - - 一种对未被充分认可的诊断的方法
H Simon Schaaf1, Adrie Bekker2, Helena Rabie2
1Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Frontiers in public health
|November 29, 2023
概括
婴儿周围结核病 (TB) 诊断不足,导致严重的疾病和死亡. 对于在怀孕期间暴露于结核病的婴儿,早期评估和管理至关重要.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 围产期结核病 (TB) 影响3个月以下的婴儿,经常被诊断不足,导致严重的后果.
- 结核菌的先天和产后传播对患有结核病的母亲产生的新生儿构成重大风险.
研究的目的:
- 提高对新生儿和婴儿结核病的认识.
- 为评估和管理在怀孕期间或怀孕后暴露于母乳结核病的婴儿提供指导.
主要方法:
- 对围产结核病现有文献和临床指导方针的审查.
- 分析与孕期和产后母亲结核病相关的风险.
主要成果:
- 每年大约有217,000名孕妇患有结核病,如果母亲的诊断和治疗延迟,他们的婴儿面临高风险.
- 出生于未经治疗或培养阳性结核病的母亲的婴儿需要立即对结核病或感染进行评估.
- 预防性结核病治疗或及时治疗对于暴露的婴儿至关重要,而艾滋病毒状况会影响管理.
结论:
- 临产期结核病的早期诊断和管理对于降低婴儿发病率和死亡率至关重要.
- 需要标准化指导方针来评估和治疗暴露于母乳结核病的婴儿.
- 需要进一步的研究来改善结核病的诊断,孕妇的预防,以及了解幼儿的药物药理动力学.
相关概念视频
Pulmonary Tuberculosis IV
143
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
143
Pulmonary Tuberculosis V
181
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
181
Pulmonary Tuberculosis III
336
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
336
Pulmonary Tuberculosis I
244
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
244
Pulmonary Tuberculosis II
242
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
242
Pneumonia III: Complications and Assessment
239
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
239


