在急性初级角关闭和急性初级角关闭眼之后的偏中心急性中间眼病
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, People's Republic of China.
Clinical ophthalmology (Auckland, N.Z.)
|November 29, 2023
概括
偏中心急性中间斑点病变 (PAMM) 发生在2.9%的急性初级角关闭 (APAC) 和APAC玻璃眼 (APACG) 病例中. 年轻的2型糖尿病患者和较短的轴长更容易患PAMM.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 青光眼的研究研究.
背景情况:
- 急性初级角度闭合 (APAC) 和急性初级角度闭合光眼 (APACG) 是眼科紧急情况.
- 偏中心急性中间斑点病变 (PAMM) 是一种影响斑点的疾病,可能会影响中心视力.
- APAC/APACG与PAMM的发展之间的关系需要进一步研究.
研究的目的:
- 为了确定在患有APAC或APACG的患者中PAMM的流行率.
- 描述亚太/亚太CG的二次PAMM的临床特征和阶段.
- 为了确定与这种患者群体中PAMM发展相关的风险因素.
主要方法:
- 对被诊断患有APAC或APACG的患者进行了回顾性研究.
- 基于光谱域光学连贯性断层扫描 (SD-OCT) 发现的PAMM分为三个阶段的分类.
- 分析治疗时间 (TST),视网膜厚度和最佳校正视敏度 (BCVA) 的改善.
- 用于评估PAMM风险因素的二进制物流回归模型.
主要成果:
- 在781个APAC/APACG眼中的2.9%中发现了PAMM.
- 与I阶段相比,III阶段的PAMM眼睛具有较长的TST和较薄的视网膜 (P=0.008,P<0.0001).
- 与第一阶段PAMM相比,BCVA改善在第三阶段较差 (P=0.008).
- PAMM的危险因素包括年龄较小,轴长较短,没有2型糖尿病.
结论:
- PAMM是APAC/APACG的潜在并发症,发生在2.9%的病例中.
- 视觉结果取决于阶段,早期干预与更好的BCVA改善有关.
- 年轻的患者,轴长较短的患者和2型糖尿病患者患PAMM的风险更高.
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