患有听力损失的女性表现出痴呆症风险增加和大脑缩
Megan C Fitzhugh1, Judy Pa1,2
1Department of Neurosciences University of California, San Diego La Jolla California USA.
Alzheimer's & dementia (Amsterdam, Netherlands)
|November 29, 2023
概括
听力损失增加了痴呆症的风险,特别是在女性中. 听力损失的女性也表现出更大的脑缩,这表明性别特异性机制参与了痴呆症的发展.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 流行病学 流行病学
背景情况:
- 听力损失是痴呆症的一个可改变的风险因素.
- 现有研究尚未完全阐明这种关联中潜在的性别差异.
研究的目的:
- 研究与听力损失相关的痴呆风险的性别特异性差异.
- 探索听力变化和听觉边缘区域的大脑体积变化之间的关系,检查性别差异.
主要方法:
- 利用英国生物库数据进行两项不同的研究.
- 采用Cox的比例危险模型来评估基于语音接收值的痴呆风险.
- 分析了2年的听力变化及其与听觉边缘区域大脑体积的相关性.
主要成果:
- 听力较差的女性表现出患痴呆症的风险最高.
- 听力不佳的男性没有显示出痴呆症风险增加.
- 与男性和正常听力的人相比,有听力损失的女性在听觉和边缘大脑区域的缩更大.
结论:
- 听力损失在女性中带来更大的痴呆风险和相关的大脑缩,这表明需要进行性别特定的研究.
- 社会隔离和抑郁情绪对两性痴呆风险的影响很小.
- 研究结果强调了解决听力损失的重要性,特别是在女性中,以减轻痴呆症风险.
更多相关视频
07:13Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
2.3K
06:01Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
Published on: December 9, 2022
2.5K
相关概念视频
01:30Dementia
115
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
115
01:26Alzheimer's Disease: Overview
494
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
494
01:19Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
01:27Language and Cognition
352
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
352
01:30Cognitive Development During Adulthood
119
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
119