体重调整后的腰部指数和美国老年人的认知障碍:基于人口的研究
Xiao-Tong Huang1, Xiang Lv1, Hong Jiang1
1Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in endocrinology
|November 29, 2023
概括
老年人中较高的腰与身高比率 (WWI) 与较差的认知功能有关,包括记忆和处理速度. 这一发现凸显了WWI作为老年人群认知健康的潜在指标.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 公共卫生 公共卫生
背景情况:
- 肥胖越来越被认为是老年人群认知障碍的危险因素.
- 现有的肥胖指标可能无法完全捕捉与健康结果相关的身体成分细微差别.
- 腰与身高的比率 (WWI) 是一种新的指标,用于更精确地评估身体脂肪和肌肉质量.
研究的目的:
- 调查腰与身高比率 (WWI) 与老年人的认知功能之间的关联.
- 确定第一次世界大战是否是60岁及以上成年人认知能力下降的预测因素.
主要方法:
- 利用了2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
- 包括2,764名60岁及以上的成年参与者,拥有完整的数据.
- 采用加权多重线性回归,平滑拟合曲线和通用加权模型来分析第一次世界大战和认知功能关联.
主要成果:
- 在控制混变量后,在第一次世界大战和认知测试得分之间发现了统计学上显著的负相关性.
- 在第一次世界大战中每增加1个单位,数字符号替换测试 (DSST) 得分会下降3.57分.
- 在第一次世界大战和CERAD单词回忆,延迟回忆和缩短精神测试 (AFT) 分数之间也观察到负相关性,尽管根据调整水平的意义有所不同.
结论:
- 更高的腰与身高比率 (WWI) 与老年人的认知功能较差有显著的关联.
- 第一次世界大战可能是识别有认知障碍风险的老年人的一个有价值的指标.
- 需要进一步的研究来探索第一次世界大战与认知关系背后的机制.
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