便短链脂肪酸修改了袖子胃切除术的治疗效果
Chongrong Shen1,2, Yanru Chen1,2, Qiaoling Wang1,2
1Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in endocrinology
|November 29, 2023
概括
袖子胃切除术改变了便短链脂肪酸 (SCFA),影响了代谢健康. 手术前的六酸盐和丁酸盐水平可以预测SG在减肥和改善脂质状况方面的有效性.
科学领域:
- 胃肠病学 胃肠病学
- 代谢手术 代谢手术
- 微生物组研究 微生物组研究
背景情况:
- 袖子胃切除术 (SG) 是一种常见的减肥手术,具有显著的代谢益处.
- 便短链脂肪酸 (SCFA) 在调解这些益处中的作用尚未完全理解.
- 研究手术前的SCFA概况可能会揭示SG结果的预测标记.
研究的目的:
- 为了检查在SG之后便SCFA的变化.
- 确定SCFA变化与SG后代谢改善之间的关联.
- 评估手术前的SCFA水平是否会改变SG的治疗效果.
主要方法:
- 在SG之前和SG后6个月内,对62名参与者的便SCFA和代谢指数进行了分析.
- 对SCFA变化与代谢结果的相关性分析.
- 按手术前的SCFA水平进行分层,以评估对SG结果的修改影响.
主要成果:
- SG显著改变了便SCFA的形状.
- 酸和酸的变化与甘油三和胆固醇的改善有关.
- 手术前高水平的六酸盐预测了更好的体重,BMI,以及降低甘油三.
- 手术前低的丁酸盐预测了ALT和AST的更好降低.
结论:
- 便SCFA水平在SG后发生变化,与改善的脂质样本相关.
- 手术前便中的六酸盐和丁酸盐度是SG代谢益处的潜在预测生物标志物.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
90
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
90
Inflammatory Bowel Disease V: Surgical Management
148
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
148
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
335
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
335
Peptic Ulcer Disease V: Surgical Management and Nursing Care
309
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
309
What is Monogastric Digestion?
71.2K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.2K


