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Updated: Jul 23, 2026

Cytological Analysis of Spermatogenesis: Live and Fixed Preparations of Drosophila Testes
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RNA测序档案显示,精子生成逐渐减少,在成年人中逐渐进展到密码化

Weihao Sun1, Xinhui Zhang1, Lei Wang1

  • 1Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Frontiers in endocrinology
|November 29, 2023
PubMed
概括

在没有下降的丸 (cryptorchidism) 的男性中,生育能力随着年龄的增长而下降. 这项研究揭示了与年龄相关的组织学变化,并确定了参与精子发育的关键下调基因,为不孕机制提供了洞察力.

关键词:
有关RNA测序的RNA测序密码主义 (cryptorchidism) 是一种关于密码主义的现象.不孕不育 不孕不育 不孕不育精子的产生是精子的产生.测试 测试 测试 测试

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Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
Spermatogenesis01:22

Spermatogenesis

Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
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Development of the Sexual Organs in the Embryo and Fetus

Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...
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Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...