坑网和肠道微生物群:潜在的联系,未来的方向
Ding Nie1, Chuzhong Li1, Yazhuo Zhang1
1Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Frontiers in endocrinology
|November 29, 2023
概括
肠道微生物组通过肠-大脑轴影响中枢神经系统疾病. 这篇评论探讨了肠道微生物群.
科学领域:
- 神经内分泌学神经内分泌学
- 微生物组研究 微生物组研究
- 在瘤学瘤学.
背景情况:
- 人们越来越认识到肠道微生物组在健康和疾病中的作用.
- 微生物组-大脑-肠轴将肠道微生物与中枢神经系统功能联系起来.
- 肠道微生物影响疾病的发病,进展,症状和治疗.
研究的目的:
- 审查肠道微生物群和垂体神经内分泌瘤 (PitNETs) 之间的关系.
- 分析肠-大脑轴在PitNETs中的潜在作用.
- 介绍这个领域的未来研究方向.
主要方法:
- 文献综述侧重于肠道微生物群,肠-大脑轴,以及PitNETs.
- 对微生物群落与神经内分泌系统之间的相互作用进行现有研究的分析.
- 综合当前的知识和识别研究差距.
主要成果:
- 皮特NET与新陈代谢,内分泌学和免疫有关,这些都受到肠道微生物的影响.
- 肠-大脑轴代表了肠道微生物对PitNETs的影响的潜在途径.
- 目前关于肠道微生物对PitNET发育和进展的具体影响的研究有限.
结论:
- 肠道微生物群可能在PitNETs的发病过程中发挥重要作用.
- 对肠-大脑轴的进一步调查对于理解PitNETs至关重要.
- 未来的研究应该专注于阐明肠道微生物群与PitNET相互作用背后的机制.
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