对患有PTSD的退伍军人使用高压氧气:基本生理学和当前可用的临床数据
Keren Doenyas-Barak1,2, Ilan Kutz1, Erez Lang1,2
1Sagol Center for Hyperbaric Medicine and Research, Shamir Medical Center, Zerifin, Israel.
Frontiers in neuroscience
|November 29, 2023
概括
高压氧疗法 (HBOT) 对治疗患有持续性创伤后应激障碍 (PTSD) 的退伍军人来说是有前途的. 这种疗法可以修复大脑结构并恢复功能,改善那些对传统治疗没有反应的人的症状和日常生活.
科学领域:
- 神经科学是一个神经科学.
- 再生医学是一种再生医学.
- 高压医学的高压医学.
背景情况:
- 创伤后应激障碍 (PTSD) 影响了许多退伍军人,其中很大一部分对当前的治疗没有反应.
- 持续的PTSD症状与大脑的前临界回路中的结构和功能障碍有关.
- 有效的治疗方法可能旨在修复大脑结构并恢复神经功能.
研究的目的:
- 审查高压氧气疗法 (HBOT) 的再生生物效应.
- 讨论正在进行的关于HBOT对抗治疗PTSD的退伍军人疗效的研究.
- 探索HBOT在解决与PTSD相关的结构性和功能性大脑变化方面的潜力.
主要方法:
- 关于HBOT对大脑结构和功能的影响的当前科学文献的综述.
- 对患有PTSD的退伍军人的HBOT临床发现的分析.
- 检查HBOT提出的机制,包括基因表达,代谢变化和神经发生.
主要成果:
- 在治疗各种脑损伤,如中风和创伤性脑损伤方面,HBOT已被证明是有效的.
- 最近的研究表明,HBOT对抗治疗PTSD的退伍军人有好处,减少了侵入性思想,回避和过度兴奋等症状.
- 创伤后应激障碍症状的改善与大脑功能增强和扩散张力图像定义的结构变化相关.
结论:
- HBOT具有再生性质,可以修复大脑损伤并恢复功能.
- 对于患有抗治疗PTSD的退伍军人来说,HBOT是一个有前途的治疗途径.
- 需要进一步的研究,以充分理解和优化用于PTSD治疗的HBOT协议.
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