在分散的临床研究中,患者招募成功的方法和认知
Brian L Miyata1, Barbara Tafuto1,2, Nadina Jose1,2
1New Jersey Alliance for Clinical and Translational Science, Newark, NJ, USA.
Journal of clinical and translational science
|November 29, 2023
概括
分散的临床研究方法显著改善了患者的招募和保留. 这些方法也显示出增加参与者多样性的积极趋势,解决临床研究中的关键挑战.
科学领域:
- 临床研究方法论 临床研究方法论
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患者招募,多样性和保留对于代表性临床研究至关重要.
- 越来越多地探索分散的临床方法来克服这些挑战.
研究的目的:
- 系统地审查分散方法对临床研究招聘,保留和多样性的影响.
- 解决关于分散的临床试验有效性的可比数据的差距.
主要方法:
- 系统的文献搜索关于分散的临床试验和相关主题的研究.
- 审查专注于招聘作为主要结果的研究.
- 对二次结果的分析,包括保留,参与者多样性和满意度.
主要成果:
- 13项研究强调了去中心化方法的积极影响.
- 十一项研究报告说,招聘改善了,其中七项研究显示直接比较传统方法.
- 七项研究报告了积极的保留结果,六项研究表明人口多样性增加.
结论:
- 分散的临床方法,包括虚拟访问,可以积极影响患者的招聘和保留.
- 有证据表明,这些方法有助于在临床研究群体中增加多样性.
- 进一步的数据支持采用分散的方法,使临床研究更具包容性和效率.
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