使用行为科学来增强试验中核心结果集的使用:协议
Karen Matvienko-Sikar1, Molly Byrne2, Mike Clarke3
1School of Public Health, University College Cork, Cork, Ireland.
HRB open research
|November 29, 2023
概括
本研究确定了通过了解影响其采用的行为因素来增加临床试验中核心结果集 (COS) 的使用的策略. 目标是减少研究浪费,改善证据综合.
科学领域:
- 临床试验方法论 临床试验方法论
- 医疗服务研究 医疗服务研究
- 行为科学是一种行为科学.
背景情况:
- 核心结果集 (COS) 对于在临床试验中标准化结果测量,减少异质性和研究浪费至关重要.
- 尽管有好处,但试验中COS的采用率仍然很低,这表明它们的使用存在行为因素.
- 了解影响试验者的行为因素对于改善COS实施至关重要.
研究的目的:
- 识别基于理论的行为策略,以加强在临床试验中使用核心结果集 (COS).
- 通过检查潜在的行为决定因素来解决COS的低吸收问题.
- 通过增加COS利用来促进更一致和更有效的证据综合.
主要方法:
- 采用行为变化轮 (BCW) 框架来指导战略制定.
- 第一个阶段:通过综合已发表的文献来识别COS使用的障碍和推动因素,并将其映射到COM-B模型 (能力,机会,动机).
- 第二阶段:根据第一阶段的发现,选择干预功能和行为改变技术,以促进COS的采用.
主要成果:
- 该研究将阐明阻碍或促进在临床研究中使用COS的特定行为因素.
- 结果将为制定有针对性的干预措施提供信息,以克服COS实施的障碍.
- 这项研究旨在清楚地了解如何在试验者中有效地促进COS的使用.
结论:
- 通过理解和解决试验参与者的行为方面,可以制定提高试验中COS使用的有效策略.
- 这项研究将有助于提高临床试验报告的质量和一致性.
- 通过加强COS采用,这项工作支持更强大的证据综合和减少研究浪费.
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