益生菌细菌对腹引起的细菌的协聚作用
S Rashad Hameed1, J Abdul Sattar Salman1
1Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq.
Archives of Razi Institute
|November 29, 2023
概括
这项研究评估了包括Lactobacillus和Lactococcus物种在内的益生菌细菌对抗导致腹的细菌的能力. 研究人员发现,这些益生菌对大肠杆菌和Shigella sonnei等常见病原体具有显著的抗菌和联合聚合作用.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 益生菌研究 益生菌研究
背景情况:
- 益生菌在疾病预防和治疗,特别是胃肠炎和急性腹方面有着悠久的使用历史.
- 了解益生菌通过哪些特定机制发挥它们的有益作用,对于优化它们的治疗应用至关重要.
研究的目的:
- 评估各种益生菌细菌分离物对导致腹的细菌的共同聚合能力.
- 描述选定分离物的关键益生菌性质,包括抗生素敏感性,自身聚合,粘附性,抗菌活性,以及对酸和胆汁盐的耐受性.
主要方法:
- 检测了11种益生菌分离物 (植物性乳杆菌,气性乳杆菌,发酵性乳杆菌,酸性乳杆菌,加尔维亚乳杆菌).
- 评估了抗生素易感性,自身聚合,粘附性,抗菌活性,酸耐受性和胆盐耐受性.
- 对大肠杆菌,Shigella sonnei和Providencia alcalifaciens等腹病原体进行评估的联合聚合潜力.
主要成果:
- 大多数益生菌分离物表现出自身聚合和粘附能力,在酸性和胆盐条件下具有显著的生存率.
- 对导致腹的细菌观察到显著的抗菌活性,抑制区范围为17-49毫米.
- 益生菌分离物,特别是L. fermentum和L. acidophilus,对P. alcalifaciens和其他病原体表现出强烈的联合聚合 (高达100%).
结论:
- 研究的益生菌细菌具有固有的益生菌特征,包括耐受性和抗菌作用.
- 这些益生菌显示出显著的协同聚合潜力,表明控制腹病原体的可行策略.
- 研究结果支持使用特定的乳酸菌和乳球菌菌株作为治疗腹疾病的辅助剂.
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