在IV级新生儿重症监护病房中对甲基西林耐药黄金葡萄球菌的殖民化风险因素:一项回顾性研究
Julia Elzbieta Galuszka1, Kim Thomsen2, Jenny Dahl Knudsen2
1Department of Neonatology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Antimicrobial stewardship & healthcare epidemiology : ASHE
|November 29, 2023
概括
这项研究确定了新生儿重症监护病房中抗甲基西林黄金葡萄球菌 (MRSA) 殖民的关键风险因素,包括呼吸系统疾病和侵入性手术. 这些发现为防止未来MRSA在脆弱婴儿群体中爆发的战略提供了信息.
科学领域:
- 新生儿医学 新生儿医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 耐甲基西林黄金葡萄球菌 (MRSA) 在新生儿重症监护室 (NICU) 构成重大威胁.
- 了解风险因素对于预防MRSA疫情和保护脆弱的新生儿至关重要.
研究的目的:
- 在MRSA爆发期间,确定与新生儿患者MRSA殖民相关的风险因素.
- 为尽量减少NICU中未来MRSA爆发的战略提供信息.
主要方法:
- 在IV级NICU中进行了一项回顾性病例控制研究.
- 阳性MRSA新生儿与对甲素敏感的金黄色葡萄球菌 (MSSA) 殖民的新生儿匹配1:1.
- 分析了140名患者,单位和微生物特征,以确定风险因素.
主要成果:
- 在1102名查的新生儿中,33名MRSA阳性,所有人都被疫情克隆 (spa类型t127) 殖民.
- 与MRSA殖民相关的因素包括呼吸系统疾病的入院,输管,外周静脉导管,共享房间设施和再入院.
- 12%的MRSA阳性新生儿患有严重感染.
结论:
- 临床相关的疾病,程序和设施使新生儿易患MRSA感染.
- 虽然一个特定的MRSA储存库仍然未被确定,但这些发现导致了关键的NICU变化,以减少MRSA感染和爆发.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Infection
8.0K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
8.0K
Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K


