患有糖尿病的HeFH和CAD中的E670G PCSK9多态性:通往个性化治疗的桥梁是否可达?

Rano Alieva1, Aleksandr Shek1, Alisher Abdullaev2

  • 1CAD & Atherosclerosis Department, Republican Specialized Center of Cardiology, Tashkent, Uzbekistan.

概括

PCSK9 E670G基因的G等位基因与冠状动脉疾病 (CAD) 患者的2型糖尿病 (T2DM) 风险更高有关,特别是那些患有异性家族高胆固醇血症 (HeFH) 患者. 这一发现对于了解心血管疾病患者的遗传倾向具有重要意义.

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