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Updated: Jul 9, 2025

The Logic, Experimental Steps, and Potential of Heterologous Natural Product Biosynthesis Featuring the Complex Antibiotic Erythromycin A Produced Through E. coli
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细菌甲基酸 (MEP) 路径中的进化灵活性和刚性

Bailey Marshall1,2, Kaustubh Amritkar3, Michael Wolfe1,2

  • 1Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, United States.

Frontiers in microbiology
|November 29, 2023
PubMed
概括

研究人员探索了微生物类生物合成,发现Dxs酶是灵活的,但IspG和IspH在进化上是必不可少的. 这有助于通过识别路径限制来促进可持续生产.

关键词:
进行比较的基因组学.异类生物合成异类生物合成代谢工程是代谢工程.合成生物学 合成生物学terpenoid 的生物合成.

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