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Updated: Jul 9, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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通过 [4 + 1] 无效双C-H功能化从N,N-dialkylanilines中合成N-alkylindoles

Bowen Zhang1, Frederik R Erb1, Aristidis Vasilopoulos2

  • 1Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Journal of the American Chemical Society
|November 29, 2023
PubMed
概括

这项研究引入了一种新型的C-H功能化方法,用于合成N-. N,N-dialkylanilines的高效双重取消为创建复杂的内支架提供了一个简单的途径.

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