强迫症的药物治疗:来自10年后期数据分析的现实世界证据
Sanghoon Oh1, Sunwoo Cho2, Sun-Young Moon3
1Department of Psychiatry, Seoul National University College of Medicine, Seoul, the Republic of Korea; Department of Psychiatry, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Gyeonggi-do, the Republic of Korea.
Asian journal of psychiatry
|November 29, 2023
概括
在韩国,2008年至2017年期间,对强迫症 (OCD) 的心理药物使用增加. 选择性血清素再吸收抑制剂 (SSRI) 和组合疗法是最常见的,特别是在并发症时.
科学领域:
- 精神病学是一个精神病学.
- 临床药房 临床药房
- 药理学 药理学是指药理学的学科.
背景情况:
- 强迫症 (OCD) 需要有效的药物治疗.
- 了解现实世界的处方模式对于治疗优化至关重要.
研究的目的:
- 分析2008年至2017年韩国强迫症患者的药物治疗趋势.
- 识别经常被处方的药物类别和组合疗法.
- 检查伴随性疾病对心理药物处方的影响.
主要方法:
- 追溯分析了1894年在第三级医院治疗的强迫症患者.
- 在2008年至2017年期间,收集关于精神药物处方的数据.
- 对药物类频率,组合疗法和并发症效应的统计分析.
主要成果:
- 82.9%的患者接受了精神药物治疗,随着时间的推移,处方率增加.
- 选择性血清素再吸收抑制剂 (SSRI) 是最常见的 (80.5%),其次是抗焦虑药 (57.5%) 和抗精神病药 (47.2%).
- 79.7%的接受药物治疗的患者使用组合治疗;并发症显著增加了处方率 (P < 0.001).
结论:
- 韩国强迫症的药物治疗显示出心理药物使用增加的趋势,特别是SSRI和组合疗法.
- 伴随性疾病在强迫症患者的药物选择中发挥着重要作用.
- 这些发现可以为临床实践提供信息,并弥合强迫症治疗指南和现实世界的应用之间的差距.
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