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Updated: Jul 9, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on: November 9, 2020

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针对性降解技术作为潜在的SARS-CoV-2疗法

Rabia Khurshid1, Joseph M Schulz1, Jiaming Hu1

  • 1Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Drug discovery today
|November 29, 2023
PubMed
概括

有针对性的蛋白质降解为对抗SARS-CoV-2变种提供了一种新的方法. 该战略旨在通过降解关键病毒蛋白来开发新的抗病毒疗法,从而有可能克服耐药性.

关键词:
这就是PROTAC.这就是SARS-CoV-2病毒.这是一种抗病毒药物.蛋白质酶蛋白质酶是一种蛋白质.有针对性的蛋白质降解降解.

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