相关实验视频

Updated: Jul 9, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Published on: August 23, 2019

甲状腺癌治疗中的微生物群的临床潜力

Zilan Xie¹, Jiating Zhou¹, Xuan Zhang²

¹Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha 410078, PR China; Institute of Clinical Pharmacology, Central South University; Hunan Key Laboratory of Pharmacogenetics, Changsha 410078, PR China; Engineering Research Center of Applied Technology of Pharmacogenomics, Ministry of Education, 110 Xiangya Road, Changsha 410078, PR China; National Clinical Research Center for Geriatric Disorders, 87 Xiangya Road, Changsha 410008, Hunan, PR China.

Biochimica et biophysica acta. Molecular basis of disease

|November 29, 2023

概括

肠道,口腔和甲状腺微生物群显著影响甲状腺癌的发展和治疗. 了解这些微生物群落为改善患者的治疗结果和治疗提供了新的途径.

科学领域:

内分泌学在内分泌学.
微生物学微生物学
在瘤学瘤学.

背景情况:

甲状腺癌的发病率在全球范围内不断上升,使其成为一个重要的内分泌系统瘤.
肠道,甲状腺和口腔微生物群在调节新陈代谢和免疫力方面发挥着至关重要的作用.
新兴证据将微生物群与瘤发展的各个阶段联系起来,包括形成,预防,诊断和治疗.

研究的目的:

审查口腔,肠道和甲状腺微生物群对甲状腺癌发展的影响.
讨论特定的微生物物种,它们的功能,以及与甲状腺癌有关的机制.
探索微生物组调制增强甲状腺癌治疗的潜力.

主要方法:

文献综述综合了当前关于微生物群和甲状腺癌的研究.
分析详细介绍微生物物种,功能和机制的研究.
探索微生物群在免疫疗法和放射性治疗中的作用.

主要成果:

特定的口腔,肠道和甲状腺微生物群落与甲状腺癌的发展有关.
微生物群影响关键的生物过程,与瘤发生有关.
微生物组的组成会影响现有的甲状腺癌治疗的疗效.

结论:

肠道,口腔和甲状腺微生物群是甲状腺癌的关键因素.
准微生物组是改善甲状腺癌治疗有效性的有希望的策略.
调节微生物组有可能提高免疫疗法和放射性治疗的结果.

关键词:

便移植便移植免疫系统的免疫系统.代谢过程中的代谢.微生物群中的微生物群放射性治疗是一种放射性治疗.甲状腺癌是什么?甲状腺癌是什么?

更多相关视频

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

相关概念视频

The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...